Small animal imaging studies and their prospects
نویسندگان
چکیده
منابع مشابه
Design of Small Animal Computed Tomography Imaging for in vitro and in vivo Studies
Introduction: Mini Computed Tomography (mini-CT) was suggested in biomedical research to investigate tissues and small animals. We present designed and built a mini x-ray computed tomography (mini-CT) for small animals as well as industrial component imaging. Materials and Methods: The system used in this study includes a X-ray tube 20kV to 160kV and a flat pa...
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The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to commercial translation to clinical practice. Whole-body small animal imaging is a particularly elegant and cost-effective experimental platform for the timely validation and commercialization of novel agents from the bench to the bedside. Biomedical imaging...
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Positron emission tomography (PET) is well established as an important research and clinical molecular imaging modality. Although the size differences between humans and rodents create formidable challenges for the application of PET imaging in small animals, advances in technology over the past several years have enabled the translation of this imaging modality to preclinical applications. In ...
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PURPOSE Presence of photon attenuation severely challenges quantitative accuracy in single-photon emission computed tomography (SPECT) imaging. Subsequently, various attenuation correction methods have been developed to compensate for this degradation. The present study aims to implement an attenuation correction method and then to evaluate quantification accuracy of attenuation correction in s...
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UNLABELLED Recent developments have established molecular imaging of mouse models with small-animal PET and bioluminescence imaging (BLI) as an important tool in cancer research. One of the disadvantages of these imaging modalities is the lack of anatomic information. We combined small-animal PET and BLI technology with small-animal CT to obtain fusion images with both molecular and anatomic in...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2016
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.147.161